The problem for Logitech's more expensive remotes is that the software used to set them up is identical to that of the cheaper 555.
It's the main draw of the Harmony range – a substantial yet brilliantly intuitive setup that correctly identifies even the newest products without any trial-and-error testing of codes.
Luckily, the One justifies its premium with a sleeker, more ergonomic design, a vibrant, full-colour touchscreen, and a dedicated charge cradle.
And this model is also now designated Harmony One+, indicating you can use it with the new MyHarmony.com web interface. But then you can use the nonplussed(!) One with the same interface, so...
Admittedly we're not keen on the decision to move the colour buttons from the chassis to the screen (they're out of the way too much considering how frequently they're used), but that's the only downside.